Here are photos after the thread lifting and Ultherapy procedures. The thread lifting showed immediate results haha. The accessibility is good, and they take great care of the procedure.

Seomyeon, Busan · Filler-focused aesthetic clinic
At Barog Clinic in Seomyeon, Busan, Re2O is a skin booster made from human-derived extracellular matrix (hADM), injected to supplement the dermis directly for glow, finer-looking pores, and elasticity. It is not an exosome and not a PLLA collagen stimulator. Skin boosters are usually done as a short course, with the exact schedule set at consultation; expect small injection marks and mild redness for a day or two. Per-session pricing is posted on this page.
Re2O is a skin booster built from human-derived extracellular matrix, so it supplements the dermal building blocks directly without needing to trigger a reaction. Patients come to it for water-glow skin, finer-looking pores, and a firmer surface. It is not an exosome and not a PLLA stimulator, and this page keeps that distinction plain.

Re2OThe injectable is placed as a layer in the upper dermis, supporting a denser collagen network and a smoother surface for dull-looking skin.
Illustration for explanation only. Results differ from person to person.Re2O is an hADM extracellular-matrix skin booster for skin quality. These are the goals it is planned around, and the situations where treatment is moved.
Anticoagulant use must be disclosed, because it raises bruising risk. If your priority is deeper structural volume, the filler menu is the more direct route.

Your doctor
Director · Filler & contouring lead
Three physicians. One standard.KMLE licence no. 127092. Restylane Expert Member, Belotero and Byryzn Key Doctor.
Skin boosters get lumped together in marketing, but the material inside them is what decides how they behave. Re2O is built from human-derived acellular dermal matrix, meaning it supplies extracellular-matrix components, the structural proteins your dermis is made of, directly into the skin. The idea is supplementation over provocation: it tops up the dermal scaffolding directly, without relying only on an inflammatory or stimulatory reaction to build it.
That places Re2O in its own lane. It is not an exosome product, and it is not a poly-L-lactic acid or PCL collagen stimulator such as those used elsewhere on the body. Patients search for it as an ECM or hADM booster and reach for it when the goal is water-glow skin, a smoother surface, and a firmer feel. Because injectable skin conditioning is a course-based idea, Re2O is usually planned as a short series across several visits, with the exact schedule set at consultation. If your priority is deeper structural volume and not skin quality, the filler menu is the more direct route.
Re2O and Rejuran are the two regenerative skin boosters patients most often weigh against each other, and the straightforward answer is that they are made of different things. Rejuran is built on salmon-derived polynucleotides, which support repair and skin quality through a different pathway. Re2O supplies human-derived extracellular-matrix components to the dermis. The clinic stocks both, which is exactly why it can walk you through the difference, with no incentive to steer you to whichever one it happens to carry.
Choosing between them is a consultation conversation, worked through with the team. Skin with a fish-protein sensitivity, for instance, is a reason to look at the non-salmon option; a preference for a particular texture outcome may point the other way. If you want the salmon-polynucleotide route instead, the Rejuran page covers it in full, and either can sit alongside a lift such as a PDO thread lift for skin quality plus repositioning.
Sixteen authenticity and quantity certificates from filler, injectable, and device manufacturers hang in the clinic. The practical version matters more than the wall: the Re2O vial is unsealed at the chair, and the volume you are billed for is the volume placed. KHIDI registration for international patients is in place at the clinic, its English-language certificate posted on site. Over 10,000 Re2O cases have been logged here since 2021, the kind of volume that lets the team speak from experience about who does well with it.
The medical team looks at your skin quality, pore appearance, and elasticity, confirms an ECM booster fits your goal better than a filler or a stimulator would, and plans the course. Whether Re2O or a salmon-polynucleotide booster suits you better is discussed here, and refusal criteria are screened before booking.
Numbing cream is applied while the Re2O vial is brought out sealed. It is opened at the chair, so the volume billed matches the volume placed, and the treatment area is cleaned and mapped.
The material is placed across the treatment area in fine microinjections at consistent depth, which is what spreads the ECM supplementation evenly through the skin. A session typically takes 20 to 30 minutes depending on the area covered.
Cooling is applied, and you leave with plain instructions: keep the area clean, skip heavy makeup, saunas, and vigorous exercise for a day or two. Because skin boosters build over a series, the next session in the planned course is scheduled before you leave, so the series never drifts.
| Option | Material | How it works | Goal it suits |
|---|---|---|---|
| Re2O | Human-derived extracellular matrix (hADM) | Supplies dermal building blocks directly | Glow, finer-looking pores, a firmer surface |
| Rejuran | Salmon-derived polynucleotides | Supports repair through a different pathway | Skin quality, for those choosing the salmon route |
| Filler | Structural volumizer | Adds volume where placed | Deeper structural volume, not skin quality |
The clinic stocks both boosters, and the choice is worked through at consultation.
Re2O is priced per session, with the volume per visit set by skin condition and area at consultation. The board below mirrors the clinic's posted list; figures render in KRW with an approximate USD conversion.
Re2O ECM skin booster, per session, volume set at consultation
A short course is usually planned rather than a single visit
from₩590,000excluding VAT (10% VAT is added at payment)Book NowSame price for international patients · Availability confirmed at consultation
Prices from the clinic's official boards, VAT excluded. Same price for international patients. Event items are this month's (October 2026) — new board every month. Availability confirmed at consultation.
Fine microinjections take 20 to 30 minutes depending on the area, then cooling is applied.
Keep the area clean; skip heavy makeup, saunas and vigorous exercise.
Small injection marks, redness and mild swelling or a bump-like feel settle within one to three days.
The next session is scheduled before you leave; improvement is gradual across sessions.
Small marks and redness for one to three days.
A bump-like feel can last one to three days.
Occasional; anticoagulants raise the risk, so disclose them.
Active infection or inflammation in the area means treatment is postponed.
A known allergy to the components is screened before booking.
Re2O works over a course, so expect improvement across sessions, not an overnight change.
Four published studies provide context for injectable dermal skin conditioning and its safe management as a treatment class. They describe the class, not Re2O specifically:
These citations describe injectable dermal skin conditioning and its complication management as a treatment class; they were not conducted on Re2O. Re2O's own material identity, an hADM-derived extracellular matrix, is stated from the clinic's product information, and individual outcomes vary with skin condition and the course completed.
Here are photos after the thread lifting and Ultherapy procedures. The thread lifting showed immediate results haha. The accessibility is good, and they take great care of the procedure.
I visit this clinic at least once a month these days because I'm going through a skin slump. The biggest advantage is that you can get treatment right away without an appointment! As someone with an unpredictable schedule, I consider this…
Great location! Plus, there's hardly any waiting time, and everything is done quickly and efficiently, which is great because it saves me time compared to how often I used to spend at clinics! I've given it 5 stars because I'm hoping for…
Director Park Sung-kyu is meticulous and has great taste in his procedures, so I trust him completely and always entrust my face only to Barogeu Clinic Seomyeon Branch. I will definitely recommend the Seomyeon Branch to my family and…
院長さんがすごく優しくて手早いので安心して施術をもらいました❤️カウンセリングも無理なアップセルなしで行ったので、希望の施術だけもらうことが可能でした😆また次回来院します🍀
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The clinic is on the 2nd and 3rd floors of 9 Jungang-daero 691beon-gil, Busanjin-gu, minutes on foot from Seomyeon Station at the crossing of Busan's two principal subway lines. Doors are open 10:00 to 20:00 on weekdays, 10:00 to 16:00 on Saturday, and shut on Sunday. Re2O has little downtime beyond a day or two of small marks and mild redness, which makes it easy to fit into a trip; because it works best as a course, travelers sometimes start it here and continue a comparable booster at home. Evening slots until 8pm let you treat after a day out.
Related options: Rejuran salmon-polynucleotide booster compared with Re2O, a PDO thread lift for repositioning alongside skin quality, or the full filler menu for structural volume. · All lifting · LinearFirm lifting
Registered with KHIDI as a medical institution for international patients; English registration certificate displayed at the clinic.