◢  Registered foreign-patient clinic (KHIDI) · Seomyeon Station, Busan
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Barog Clinic — marble lobby, Seomyeon Busan

Seomyeon, Busan · Filler-focused aesthetic clinic

Re2O Injection in Seomyeon, Busan: an hADM skin booster

Dr. Seongkyu ParkDirector · Filler & contouring lead
590Documented before & after cases
100K+Facial filler treatments since 2021
₩590,000From — price on the board
16Authenticity certificates displayed

Quick Answer: Cost, What It Is, What to Expect

At Barog Clinic in Seomyeon, Busan, Re2O is a skin booster made from human-derived extracellular matrix (hADM), injected to supplement the dermis directly for glow, finer-looking pores, and elasticity. It is not an exosome and not a PLLA collagen stimulator. Skin boosters are usually done as a short course, with the exact schedule set at consultation; expect small injection marks and mild redness for a day or two. Per-session pricing is posted on this page.

Re2O is a skin booster built from human-derived extracellular matrix, so it supplements the dermal building blocks directly without needing to trigger a reaction. Patients come to it for water-glow skin, finer-looking pores, and a firmer surface. It is not an exosome and not a PLLA stimulator, and this page keeps that distinction plain.

Re2O: The injectable is placed as a layer in the upper dermis, supporting a denser collagen network and a smoother surface for dull-looking skin.

Re2OThe injectable is placed as a layer in the upper dermis, supporting a denser collagen network and a smoother surface for dull-looking skin.

Illustration for explanation only. Results differ from person to person.

Is Re2O right for you?

Re2O is an hADM extracellular-matrix skin booster for skin quality. These are the goals it is planned around, and the situations where treatment is moved.

Often a good fit

  • Wanting water-glow skin
  • Pores you want to look finer
  • Elasticity and a firmer feel to the surface
  • A smoother skin surface
  • A fish-protein sensitivity, pointing to a non-salmon booster
  • Skin quality alongside a lift such as a PDO thread lift

Declined or postponed

  • Pregnancy or breastfeeding
  • Active infection or inflammation in the treatment area
  • A known allergy to the injected components
  • An active autoimmune condition, discussed before treatment

Anticoagulant use must be disclosed, because it raises bruising risk. If your priority is deeper structural volume, the filler menu is the more direct route.

Dr. Seongkyu Park

Your doctor

Dr. Seongkyu Park

Director · Filler & contouring lead

Three physicians. One standard.KMLE licence no. 127092. Restylane Expert Member, Belotero and Byryzn Key Doctor.

100,000+Filler treatments
3Brand recognitions
16Certificates
  • DirectorDr. Seongkyu Park · filler & contouring · licence 127092
  • PhysicianDr. Woori Ryu · Anesthesiology & Pain Medicine specialist · lifting & energy devices · licence 78609
  • PhysicianDr. Seohee Choi · skin boosters & laser toning · licence 140105
  • RestylaneExpert Member · BeloteroKey Doctor · ByryznKey Doctor
  • KHIDIRegistered foreign-patient clinic M-2024-02-08-8151
View →
02Treatment guide

What Re2O Actually Is: An hADM Extracellular-Matrix Skin Booster

Skin boosters get lumped together in marketing, but the material inside them is what decides how they behave. Re2O is built from human-derived acellular dermal matrix, meaning it supplies extracellular-matrix components, the structural proteins your dermis is made of, directly into the skin. The idea is supplementation over provocation: it tops up the dermal scaffolding directly, without relying only on an inflammatory or stimulatory reaction to build it.

That places Re2O in its own lane. It is not an exosome product, and it is not a poly-L-lactic acid or PCL collagen stimulator such as those used elsewhere on the body. Patients search for it as an ECM or hADM booster and reach for it when the goal is water-glow skin, a smoother surface, and a firmer feel. Because injectable skin conditioning is a course-based idea, Re2O is usually planned as a short series across several visits, with the exact schedule set at consultation. If your priority is deeper structural volume and not skin quality, the filler menu is the more direct route.

Re2O vs Rejuran: Two Regenerative Boosters, Different Materials

Re2O and Rejuran are the two regenerative skin boosters patients most often weigh against each other, and the straightforward answer is that they are made of different things. Rejuran is built on salmon-derived polynucleotides, which support repair and skin quality through a different pathway. Re2O supplies human-derived extracellular-matrix components to the dermis. The clinic stocks both, which is exactly why it can walk you through the difference, with no incentive to steer you to whichever one it happens to carry.

Choosing between them is a consultation conversation, worked through with the team. Skin with a fish-protein sensitivity, for instance, is a reason to look at the non-salmon option; a preference for a particular texture outcome may point the other way. If you want the salmon-polynucleotide route instead, the Rejuran page covers it in full, and either can sit alongside a lift such as a PDO thread lift for skin quality plus repositioning.

How the Clinic Handles the Re2O Vial: Certified and Opened in Front of You

Sixteen authenticity and quantity certificates from filler, injectable, and device manufacturers hang in the clinic. The practical version matters more than the wall: the Re2O vial is unsealed at the chair, and the volume you are billed for is the volume placed. KHIDI registration for international patients is in place at the clinic, its English-language certificate posted on site. Over 10,000 Re2O cases have been logged here since 2021, the kind of volume that lets the team speak from experience about who does well with it.

03The appointment

Re2O injection appointment at Barog Clinic, Seomyeon, Busan

01

Skin consultation

The medical team looks at your skin quality, pore appearance, and elasticity, confirms an ECM booster fits your goal better than a filler or a stimulator would, and plans the course. Whether Re2O or a salmon-polynucleotide booster suits you better is discussed here, and refusal criteria are screened before booking.

02

Numbing and product check

Numbing cream is applied while the Re2O vial is brought out sealed. It is opened at the chair, so the volume billed matches the volume placed, and the treatment area is cleaned and mapped.

03

Injection

The material is placed across the treatment area in fine microinjections at consistent depth, which is what spreads the ECM supplementation evenly through the skin. A session typically takes 20 to 30 minutes depending on the area covered.

04

Aftercare and course plan

Cooling is applied, and you leave with plain instructions: keep the area clean, skip heavy makeup, saunas, and vigorous exercise for a day or two. Because skin boosters build over a series, the next session in the planned course is scheduled before you leave, so the series never drifts.

Re2O, Rejuran and filler at the clinic
OptionMaterialHow it worksGoal it suits
Re2OHuman-derived extracellular matrix (hADM)Supplies dermal building blocks directlyGlow, finer-looking pores, a firmer surface
RejuranSalmon-derived polynucleotidesSupports repair through a different pathwaySkin quality, for those choosing the salmon route
FillerStructural volumizerAdds volume where placedDeeper structural volume, not skin quality

The clinic stocks both boosters, and the choice is worked through at consultation.

01Transparent pricing

Re2O Price in Korea: What the Board Shows

Re2O is priced per session, with the volume per visit set by skin condition and area at consultation. The board below mirrors the clinic's posted list; figures render in KRW with an approximate USD conversion.

Re2O Injection · Barog ClinicKRW · VAT 10% EXCL.

Re2O ECM skin booster, per session, volume set at consultation

A short course is usually planned rather than a single visit

from₩590,000excluding VAT (10% VAT is added at payment)Book Now
Board prices exclude 10% VAT, matching the clinic's posted price list.

Same price for international patients · Availability confirmed at consultation

Promotions

This month's price boards

The boards, as posted.

Director's picks + this month's event list · Tap a board to enlarge · Swipe or use the tabs
←
→
Director's Best · Virtue RFKRW · VAT 10% EXCL.
Virtue RF microneedling 440 shots 1 session · 3 sessions ₩1,200,000 · 10 sessions ₩3,500,000
₩500,000
Virtue RF microneedling 220 shots 1 session · 3 sessions ₩990,000 · 10 sessions ₩2,500,000
₩350,000
Virtue RF 440 shots + Rejuran 1 session · 3 sessions ₩1,700,000
₩650,000
Virtue RF 220 shots + Rejuran 1 session · 3 sessions ₩1,200,000
₩500,000
Add-on: full-face skin toxin — brand options
₩100,000
Virtue RF non-surgical eye lift 1 session · 3 sessions ₩900,000 · 5 sessions ₩1,400,000
₩350,000
Eye-area Virtue RF + Rejuran 1 session · regular price ₩300,000
₩220,000
The clinic's No.1 recommended treatment
Potenza · Skin BoostersOCT EVENT · VAT EXCL.
Potenza trial — 1 session no expiry · can be bought more than once · needle tip +₩40,000 · pumping tip +₩50,000
₩79,000
Potenza (pumping tip incl.) + Juvelook Skin 4 cc or ByRyzn hydrating booster 2 cc + LDM 1 session · 3 sessions ₩1,190,000
₩490,000
October event · Oct 1 – 31
October ₩1,000,000 Special · Choose 1OCT EVENT · VAT EXCL.
Ear filler — Juvederm 4 cc
₩1,000,000
Hip-dip filler 50 cc
₩1,000,000
ByRyzn hydrating booster 2 cc + Dermashine tip + hydration care ×3
₩1,000,000
Ruby laser + Excel V + Genesis ×5
₩1,000,000
Alltite 400 shots + Rejuran 2 cc + skin botulinum toxin or LDM
₩1,000,000
LinearFirm (linear HIFU) 600 shots ×3
₩1,000,000
October only · choose one option
Ultherapy PrimeOCT EVENT · VAT EXCL.
Ultherapy Prime 800 shots shots can be split across visits
₩1,990,000
Ultherapy Prime 1,200 shots shots can be split across visits
₩2,820,000
October event · Oct 1 – 31
Signature Devices · StandardSTANDARD BOARD · VAT EXCL.
Ulthera Prime (Ultherapy) 100 shots · 300 ₩850,000 · 600 ₩1,500,000
₩300,000
Thermage FLX 600 shots
₩1,790,000
Shurink Universe (Ultraformer MPT) 100 shots · 600 ₩330,000 · 900 ₩450,000
₩60,000
Shurink HIFU 100 shots · 600 ₩148,000 · 900 ₩198,000
₩27,000
Oligio RF 100 shots · 300 ₩390,000 · 600 ₩690,000
₩150,000
InMode FX/FM 1 area · full face ₩250,000
₩59,000
Standard prices · 10+ more energy devices on site
SkincareOCT EVENT · VAT EXCL.
Beauty toning + Genesis + plasma + vitamin care + modeling mask 3 sessions
₩390,000
Milk peel + whitening ampoule + vitamin care + glutathione IV drip 1 session · 3 sessions ₩399,000
₩99,000
October event · Oct 1 – 31
Nose & Double ChinOCT EVENT · VAT EXCL.
Imported nose filler + HIKO nose thread lift (4 threads)
₩390,000
Wonder V fat-dissolving injection 2 cc + Miglow 40 kJ double chin
₩440,000
October event · Oct 1 – 31
Hair Removal · 1st-Session TrialOCT EVENT · women & men, same price · VAT EXCL.
Underarms or upper lip
₩9,000
Full arms
₩49,000
Full legs
₩69,000
Full face
₩79,000
Brazilian perianal area not included
₩99,000
October event · Oct 1 – 31
Director's Best
Potenza
₩1M Pick
Ultherapy
Ulthera · Thermage
Skincare
Nose & Chin
Hair Removal

Prices from the clinic's official boards, VAT excluded. Same price for international patients. Event items are this month's (October 2026) — new board every month. Availability confirmed at consultation.

Recovery, day by day

  1. Same day

    Treatment

    Fine microinjections take 20 to 30 minutes depending on the area, then cooling is applied.

  2. First day or two

    Aftercare

    Keep the area clean; skip heavy makeup, saunas and vigorous exercise.

  3. Up to three days

    Marks and swelling

    Small injection marks, redness and mild swelling or a bump-like feel settle within one to three days.

  4. Across the course

    Next session

    The next session is scheduled before you leave; improvement is gradual across sessions.

Risks and how they are handled

04Clinical evidence

What Peer-Reviewed Studies Say About Injectable Dermal Skin Conditioning

Four published studies provide context for injectable dermal skin conditioning and its safe management as a treatment class. They describe the class, not Re2O specifically:

Hyaluronic acid: A key molecule in skin aging. Dermato-Endocrinology, 2012. doi:10.4161/derm.21923
Cohesive Polydensified Matrix Hyaluronic Acid for Fine Lines. Plastic and Reconstructive Surgery, 2015. doi:10.1097/PRS.0000000000001835
Complication Management following Rejuvenation Procedures with Hyaluronic Acid Fillers. Plastic and Reconstructive Surgery Global Open, 2018. doi:10.1097/GOX.0000000000002061
Ultrasound to improve the safety of hyaluronic acid filler treatments. Journal of Cosmetic Dermatology, 2018. doi:10.1111/jocd.12726

These citations describe injectable dermal skin conditioning and its complication management as a treatment class; they were not conducted on Re2O. Re2O's own material identity, an hADM-derived extracellular matrix, is stated from the clinic's product information, and individual outcomes vary with skin condition and the course completed.

06Quick answers

Re2O Injection FAQ: Questions from International Patients

How much does a Re2O injection cost in Korea at Barog Clinic?
Re2O is priced per session starting at ₩590,000, with the volume per visit set by your skin condition and area at consultation. Because skin boosters usually work as a short course, the clinic plans the number of sessions with you and never quotes one visit blind. All board prices exclude 10% VAT.
What is Re2O exactly?
Re2O is a skin booster made from human-derived acellular dermal matrix, so it supplies extracellular-matrix components, the structural proteins of your dermis, directly into the skin. It is not an exosome product and not a PLLA or PCL collagen stimulator. Patients use it for water-glow skin, finer-looking pores, and a firmer surface.
How is Re2O different from Rejuran?
They are made of different materials. Rejuran is built on salmon-derived polynucleotides; Re2O supplies human-derived extracellular-matrix components. Both are regenerative skin boosters, and the clinic stocks both, so it can match you to the right one at consultation. A salmon-protein sensitivity, for example, is a reason to consider the non-salmon option.
Is Re2O an exosome treatment?
No. Exosome products are a separate category. Re2O is an hADM-derived extracellular-matrix booster that supplements the dermal building blocks directly. Keeping these straight matters, because they work by different mechanisms and are not interchangeable despite both being marketed as regenerative.
How many Re2O sessions will I need?
Skin boosters are usually done as a short course of several visits, and the exact number for Re2O is set at consultation based on your skin condition and goal, and settled there before you start. The clinic plans the series with you and schedules the next session before you leave so the course stays on track.
Does a Re2O injection hurt?
Numbing cream is applied first, so most patients report only minor stinging from the fine microinjections and little real pain. A session runs about 20 to 30 minutes depending on the area. Tell the team if you are sensitive and more numbing time can be added before starting.
What is the downtime after Re2O?
Little. Expect small injection marks, mild redness, and sometimes a slight bump-like feel for one to three days, with occasional bruising. Keeping the area clean and skipping heavy makeup, saunas, and vigorous exercise for a day or two is the usual advice. Most people return to normal activity the same day.
What are the real risks of Re2O?
The common effects are small injection marks, redness, and mild swelling for a day or two. Less common are bruising and, rarely, infection or a hypersensitivity reaction. It is screened against pregnancy, active infection at the site, active autoimmune conditions, and anticoagulant use, all of which are covered at consultation.
When will I see results from Re2O?
Skin boosters build gradually over a course, with no single decisive pass, so improvement in glow, pore appearance, and firmness tends to show across sessions and in the weeks after. If someone promises an instant transformation from a single skin-booster session, treat that as a red flag, never a benchmark.
Can I combine Re2O with a lift or filler?
Yes. Re2O addresses skin quality, so it sits comfortably alongside treatments that address structure or sag, such as a PDO thread lift or hyaluronic acid filler. The sequence and spacing are planned at consultation so each treatment has room to settle without piling downtime on top of downtime.
How many days should I plan in Busan for Re2O?
A single session is quick, about 20 to 30 minutes with minimal downtime, so it fits easily into a day. Because Re2O works best as a course, travelers sometimes start it in Busan and continue a comparable booster at home. Weekday hours run to 8pm, which suits fitting a session around sightseeing.
How do I know the Re2O is authentic?
Sixteen authenticity and quantity certificates from filler, injectable, and device manufacturers are displayed at the clinic, and each Re2O vial is unsealed at the chair so the volume billed matches the volume placed. The clinic is additionally registered with KHIDI for international patients, a status carrying liability insurance and documented standards.
Is Busan a good place for Re2O compared with Seoul?
Busan runs fewer international clinics than Seoul, and that is the practical advantage: Seomyeon, Busan sits on the main subway crossing with KTX and airport rail nearby, weekday evenings stay open until 8pm, and the clinic has logged over 10,000 Re2O cases since 2021. Shorter waits, the same regenerative skin booster.
Show more questions +
Google Reviews

What our patients say.

5.0 ★★★★★ 48 Google reviews · Barog Clinic Seomyeon
★★★★

Here are photos after the thread lifting and Ultherapy procedures. The thread lifting showed immediate results haha. The accessibility is good, and they take great care of the procedure.

지인김3 weeks ago · Translated by Google
★★★★★

I visit this clinic at least once a month these days because I'm going through a skin slump. The biggest advantage is that you can get treatment right away without an appointment! As someone with an unpredictable schedule, I consider this…

츄A month ago · Translated by Google
★★★★★

Great location! Plus, there's hardly any waiting time, and everything is done quickly and efficiently, which is great because it saves me time compared to how often I used to spend at clinics! I've given it 5 stars because I'm hoping for…

belle3 weeks ago · Translated by Google
★★★★★

Director Park Sung-kyu is meticulous and has great taste in his procedures, so I trust him completely and always entrust my face only to Barogeu Clinic Seomyeon Branch. I will definitely recommend the Seomyeon Branch to my family and…

박현희In the last week · Translated by Google
★★★★★

院長さんがすごく優しくて手早いので安心して施術をもらいました❤️カウンセリングも無理なアップセルなしで行ったので、希望の施術だけもらうことが可能でした😆また次回来院します🍀

하주희A week ago · Original in Japanese

Verified reviews from our Google Business Profile — the rating and count refresh daily.

Plan your Re2O appointment in Seomyeon, Busan

Message the clinic on WhatsApp to hold a weekday evening slot and get a course plan at consultation.

07BOOK A CONSULTATION

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SEOMYEON STN · 2 MIN
08Visit us

Getting Re2O in Busan: Access from Seomyeon Station, and Hours

The clinic is on the 2nd and 3rd floors of 9 Jungang-daero 691beon-gil, Busanjin-gu, minutes on foot from Seomyeon Station at the crossing of Busan's two principal subway lines. Doors are open 10:00 to 20:00 on weekdays, 10:00 to 16:00 on Saturday, and shut on Sunday. Re2O has little downtime beyond a day or two of small marks and mild redness, which makes it easy to fit into a trip; because it works best as a course, travelers sometimes start it here and continue a comparable booster at home. Evening slots until 8pm let you treat after a day out.

Mon – Fri10:00 – 20:00 OPEN LATE
Saturday10:00 – 16:00
SundayClosed
2nd–3rd fl, 9 Jungang-daero 691beon-gil, Busanjin-gu, Busan, Korea
Walkable from Seomyeon Station · 30 min from Gimhae Airport
Surrounded by Seomyeon hotels, cafés and shopping

Related options: Rejuran salmon-polynucleotide booster compared with Re2O, a PDO thread lift for repositioning alongside skin quality, or the full filler menu for structural volume. · All lifting · LinearFirm lifting

Government-registered for international patients.

Registered with KHIDI as a medical institution for international patients; English registration certificate displayed at the clinic.

Foreign patient medical institution registration — Barog Clinic
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